BDBM50154584 6-Fluoro-quinolin-2-ylamine::CHEMBL185917

SMILES: Nc1ccc2cc(F)ccc2n1

InChI Key: InChIKey=DSROYDXRWJWKRT-UHFFFAOYSA-N

Data: 2 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50154584 (6-Fluoro-quinolin-2-ylamine | CHEMBL185917) Show SMILES Nc1ccc2cc(F)ccc2n1 Show InChI InChI=1S/C9H7FN2/c10-7-2-3-8-6(5-7)1-4-9(11)12-8/h1-5H,(H2,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.28E+6	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Binding affinity to BACE1 by surface plasmon resonance method				J Med Chem 55: 678-87 (2012) Article DOI: 10.1021/jm201441k BindingDB Entry DOI: 10.7270/Q2Q81F2J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase (Mus musculus)	BDBM50154584 (6-Fluoro-quinolin-2-ylamine | CHEMBL185917) Show SMILES Nc1ccc2cc(F)ccc2n1 Show InChI InChI=1S/C9H7FN2/c10-7-2-3-8-6(5-7)1-4-9(11)12-8/h1-5H,(H2,11,12)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM50154584 (6-Fluoro-quinolin-2-ylamine | CHEMBL185917) Show SMILES Nc1ccc2cc(F)ccc2n1 Show InChI InChI=1S/C9H7FN2/c10-7-2-3-8-6(5-7)1-4-9(11)12-8/h1-5H,(H2,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Binding affinity to BACE1 by NMR-based differential chemical shift perturbation method				J Med Chem 55: 678-87 (2012) Article DOI: 10.1021/jm201441k BindingDB Entry DOI: 10.7270/Q2Q81F2J
					More data for this Ligand-Target Pair