BDBM50154587 6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine::CHEMBL366327

SMILES: Nc1ccc2cc(ccc2n1)C1OCCO1

InChI Key: InChIKey=SDBWCDHRWIANND-UHFFFAOYSA-N

Data: 1 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nck adaptor protein 1 (Homo sapiens (Human))	BDBM50154587 (6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine | CHEMBL36...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCO1 Show InChI InChI=1S/C12H12N2O2/c13-11-4-2-8-7-9(1-3-10(8)14-11)12-15-5-6-16-12/h1-4,7,12H,5-6H2,(H2,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TEC (Mus musculus)	BDBM50154587 (6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine | CHEMBL36...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCO1 Show InChI InChI=1S/C12H12N2O2/c13-11-4-2-8-7-9(1-3-10(8)14-11)12-15-5-6-16-12/h1-4,7,12H,5-6H2,(H2,13,14)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TEC (Mus musculus)	BDBM50154587 (6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine | CHEMBL36...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCO1 Show InChI InChI=1S/C12H12N2O2/c13-11-4-2-8-7-9(1-3-10(8)14-11)12-15-5-6-16-12/h1-4,7,12H,5-6H2,(H2,13,14)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair