BDBM50154592 3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-one::3-(2-oxo-2-phenylethylidene)indolin-2-one::CHEMBL190880

SMILES: O=C(\C=C1/C(=O)Nc2ccccc12)c1ccccc1

InChI Key: InChIKey=HYHFPMWIIOXTBM-RAXLEYEMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase Pfmrk (Plasmodium falciparum)	BDBM50154592 (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) Show SMILES O=C(\C=C1/C(=O)Nc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H11NO2/c18-15(11-6-2-1-3-7-11)10-13-12-8-4-5-9-14(12)17-16(13)19/h1-10H,(H,17,19)/b13-10-	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Walter Reed Army Institute of Research Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum cyclin-dependent kinase				J Med Chem 47: 5418-26 (2004) Article DOI: 10.1021/jm040108f BindingDB Entry DOI: 10.7270/Q2BZ66TW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (Homo sapiens (Human))	BDBM50154592 (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) Show SMILES O=C(\C=C1/C(=O)Nc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H11NO2/c18-15(11-6-2-1-3-7-11)10-13-12-8-4-5-9-14(12)17-16(13)19/h1-10H,(H,17,19)/b13-10-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Competitive inhibition of recombinant TAK1-TAB1 assessed as [33P]gamma-ATP incorporation into substrate histone H1 peptide by filter plate assay				Bioorg Med Chem Lett 21: 1724-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.077 BindingDB Entry DOI: 10.7270/Q2988794
					More data for this Ligand-Target Pair