BDBM50154731 7-(Hydroxy-phenyl-methyl)-3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-one::CHEMBL188308

SMILES: OC(c1cn2CCNC(=O)c3cccc1c23)c1ccccc1

InChI Key: InChIKey=PWWOQBLCBMLCNU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50154731 (7-(Hydroxy-phenyl-methyl)-3,4-dihydro-2H-[1,4]diaz...) Show SMILES OC(c1cn2CCNC(=O)c3cccc1c23)c1ccccc1 Show InChI InChI=1S/C18H16N2O2/c21-17(12-5-2-1-3-6-12)15-11-20-10-9-19-18(22)14-8-4-7-13(15)16(14)20/h1-8,11,17,21H,9-10H2,(H,19,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global R&D--La Jolla Laboratories Curated by ChEMBL					Assay Description Inhibition of human Poly (ADP-ribose) polymerase 1 enzyme				J Med Chem 47: 5467-81 (2004) Article DOI: 10.1021/jm030513r BindingDB Entry DOI: 10.7270/Q2PK0FM4
					More data for this Ligand-Target Pair