BDBM50154745 6-(4-Fluoro-phenyl)-1-oxo-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indole-7-carboxylic acid amide::CHEMBL187156

SMILES: NC(=O)c1c(-c2ccc(F)cc2)n2CCNC(=O)c3cccc1c23

InChI Key: InChIKey=NEVYJPLDJMLMLV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50154745 (6-(4-Fluoro-phenyl)-1-oxo-1,2,3,4-tetrahydro-[1,4]...) Show SMILES NC(=O)c1c(-c2ccc(F)cc2)n2CCNC(=O)c3cccc1c23 Show InChI InChI=1S/C18H14FN3O2/c19-11-6-4-10(5-7-11)15-14(17(20)23)12-2-1-3-13-16(12)22(15)9-8-21-18(13)24/h1-7H,8-9H2,(H2,20,23)(H,21,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global R&D--La Jolla Laboratories Curated by ChEMBL					Assay Description Inhibition of human Poly (ADP-ribose) polymerase 1 enzyme				J Med Chem 47: 5467-81 (2004) Article DOI: 10.1021/jm030513r BindingDB Entry DOI: 10.7270/Q2PK0FM4
					More data for this Ligand-Target Pair