null

SMILES: Fc1cc(Nc2cccnc2)cc(c1)-n1nnc(n1)-c1ccccn1

InChI Key: InChIKey=KSMWUJIVIRLPNY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50154972 (CHEMBL366333 | [3-Fluoro-5-(5-pyridin-2-yl-tetrazo...) Show SMILES Fc1cc(Nc2cccnc2)cc(c1)-n1nnc(n1)-c1ccccn1 Show InChI InChI=1S/C17H12FN7/c18-12-8-14(21-13-4-3-6-19-11-13)10-15(9-12)25-23-17(22-24-25)16-5-1-2-7-20-16/h1-11,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...				Bioorg Med Chem Lett 14: 5473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.012 BindingDB Entry DOI: 10.7270/Q2F47NMM
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50154972 (CHEMBL366333 | [3-Fluoro-5-(5-pyridin-2-yl-tetrazo...) Show SMILES Fc1cc(Nc2cccnc2)cc(c1)-n1nnc(n1)-c1ccccn1 Show InChI InChI=1S/C17H12FN7/c18-12-8-14(21-13-4-3-6-19-11-13)10-15(9-12)25-23-17(22-24-25)16-5-1-2-7-20-16/h1-11,21H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 5 in [Ca2+] flux assay using glutamate (10 uM) as agonist				Bioorg Med Chem Lett 14: 5473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.012 BindingDB Entry DOI: 10.7270/Q2F47NMM
					More data for this Ligand-Target Pair