BDBM50155605 3-Phenethyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquinoline::CHEMBL186350::CHEMBL554988
SMILES: C(Cc1ccccc1)N1CCC2=C(CCc3ccccc23)C1
InChI Key: InChIKey=CTGJCBHUIMTVHX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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D(3) dopamine receptor (Rattus norvegicus (Rat)) | BDBM50155605![]() (3-Phenethyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquino...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Binding affinity towards dopamine D3 receptor in ventral striatal membranes of sprague-dawley rat brain by using [3H]-PD 128907 as radioligand | Bioorg Med Chem Lett 14: 5813-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.047 BindingDB Entry DOI: 10.7270/Q2KP81P6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50155605![]() (3-Phenethyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair |