BDBM50155650 3,6-Di-piperidin-1-yl-acridine::CHEMBL187238

SMILES: C1CCN(CC1)c1ccc2cc3ccc(cc3nc2c1)N1CCCCC1

InChI Key: InChIKey=PMMUUHKRIUNHLH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155650 (3,6-Di-piperidin-1-yl-acridine | CHEMBL187238) Show SMILES C1CCN(CC1)c1ccc2cc3ccc(cc3nc2c1)N1CCCCC1 Show InChI InChI=1S/C23H27N3/c1-3-11-25(12-4-1)20-9-7-18-15-19-8-10-21(26-13-5-2-6-14-26)17-23(19)24-22(18)16-20/h7-10,15-17H,1-6,11-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair