BDBM50155652 3-Diethylamino-N-[6-(3-diethylamino-propionylamino)-9-oxo-9,10-dihydro-acridin-3-yl]-propionamide::CHEMBL1080436::CHEMBL362887

SMILES: CCN(CC)CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN(CC)CC)cc3nc2c1

InChI Key: InChIKey=OZPBMVWVOOUJFN-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155652 (3-Diethylamino-N-[6-(3-diethylamino-propionylamino...) Show SMILES CCN(CC)CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN(CC)CC)cc3nc2c1 Show InChI InChI=1S/C27H37N5O3/c1-5-31(6-2)15-13-25(33)28-19-9-11-21-23(17-19)30-24-18-20(10-12-22(24)27(21)35)29-26(34)14-16-32(7-3)8-4/h9-12,17-18H,5-8,13-16H2,1-4H3,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of telomerase in human A2780 cells by TRAP assay				Eur J Med Chem 44: 4826-40 (2009) Article DOI: 10.1016/j.ejmech.2009.07.029 BindingDB Entry DOI: 10.7270/Q20R9PHM
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155652 (3-Diethylamino-N-[6-(3-diethylamino-propionylamino...) Show SMILES CCN(CC)CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN(CC)CC)cc3nc2c1 Show InChI InChI=1S/C27H37N5O3/c1-5-31(6-2)15-13-25(33)28-19-9-11-21-23(17-19)30-24-18-20(10-12-22(24)27(21)35)29-26(34)14-16-32(7-3)8-4/h9-12,17-18H,5-8,13-16H2,1-4H3,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair