BDBM50155654 3,6,9-Tri-pyrrolidin-1-yl-acridine::CHEMBL184103

SMILES: C1CCN(C1)c1ccc2c(N3CCCC3)c3ccc(cc3nc2c1)N1CCCC1

InChI Key: InChIKey=IVFADSNADHLCKT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155654 (3,6,9-Tri-pyrrolidin-1-yl-acridine | CHEMBL184103) Show SMILES C1CCN(C1)c1ccc2c(N3CCCC3)c3ccc(cc3nc2c1)N1CCCC1 Show InChI InChI=1S/C25H30N4/c1-2-12-27(11-1)19-7-9-21-23(17-19)26-24-18-20(28-13-3-4-14-28)8-10-22(24)25(21)29-15-5-6-16-29/h7-10,17-18H,1-6,11-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair