BDBM50155688 2-{(Z)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but-2-enyl}-isoindole-1,3-dione::CHEMBL365201

SMILES: COc1ccccc1N1CCN(C\C=C/CN2C(=O)c3ccccc3C2=O)CC1

InChI Key: InChIKey=UTHGTZIOOOGGBI-SREVYHEPSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50155688 (2-{(Z)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but...) Show SMILES COc1ccccc1N1CCN(C\C=C/CN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H25N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-11H,12-17H2,1H3/b7-6-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50155688 (2-{(Z)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but...) Show SMILES COc1ccccc1N1CCN(C\C=C/CN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H25N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-11H,12-17H2,1H3/b7-6-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	353	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-5-CT from binding to rat 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair