BDBM50155689 2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-isoindole-1,3-dione::CHEMBL185988
SMILES: COc1ccccc1N1CCN(Cc2ccccc2CN2C(=O)c3ccccc3C2=O)CC1
InChI Key: InChIKey=AXKCFTNCUWYHCN-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin (5-HT) receptor (Rattus norvegicus (rat)) | BDBM50155689![]() (2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-b...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 367 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences Curated by ChEMBL | Assay Description In vitro ability to displace the radioligand [3H]-5-CT from binding to rat 5-hydroxytryptamine 7 receptor | Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50155689![]() (2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-b...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 405 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences Curated by ChEMBL | Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ | |||||||||||
More data for this Ligand-Target Pair |