BDBM50155693 1-{(E)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but-2-enyl}-pyrrolidine-2,5-dione::CHEMBL365412

SMILES: COc1ccccc1N1CCN(C\C=C\CN2C(=O)CCC2=O)CC1

InChI Key: InChIKey=LPHGHPDNMQWAKP-SNAWJCMRSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50155693 (1-{(E)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but...) Show SMILES COc1ccccc1N1CCN(C\C=C\CN2C(=O)CCC2=O)CC1 Show InChI InChI=1S/C19H25N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-7H,8-15H2,1H3/b5-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50155693 (1-{(E)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but...) Show SMILES COc1ccccc1N1CCN(C\C=C\CN2C(=O)CCC2=O)CC1 Show InChI InChI=1S/C19H25N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-7H,8-15H2,1H3/b5-4+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-5-CT from binding to rat 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair