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SMILES: CC(C)CC(=O)c1ccc(OCCCCOc2ccccc2F)c(C)c1O

InChI Key: InChIKey=HTQHNFJCGRDIKX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155708   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50155708
PNG
(1-{4-[4-(2-Fluoro-phenoxy)-butoxy]-2-hydroxy-3-met...)
Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccccc2F)c(C)c1O
Show InChI InChI=1S/C22H27FO4/c1-15(2)14-19(24)17-10-11-20(16(3)22(17)25)26-12-6-7-13-27-21-9-5-4-8-18(21)23/h4-5,8-11,15,25H,6-7,12-14H2,1-3H3
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Article
PubMed
n/an/an/an/a 1.99E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]-GTP gama S binding assay

Bioorg Med Chem Lett 14: 5867-72 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.028
BindingDB Entry DOI: 10.7270/Q2XW4J94
More data for this
Ligand-Target Pair