BDBM50156031 Acetic acid 2-[4-(4-chloro-phenyl)-1-methyl-piperidin-3-ylmethanesulfinyl]-ethyl ester::CHEMBL193244

SMILES: CN1CCC(C(CS(=O)CCOC(C)=O)C1)c1ccc(Cl)cc1

InChI Key: InChIKey=ZUHFHBFMBYNBLT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50156031 (Acetic acid 2-[4-(4-chloro-phenyl)-1-methyl-piperi...) Show SMILES CN1CCC(C(CS(=O)CCOC(C)=O)C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H24ClNO3S/c1-13(20)22-9-10-23(21)12-15-11-19(2)8-7-17(15)14-3-5-16(18)6-4-14/h3-6,15,17H,7-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Acenta Discovery, Inc. Curated by ChEMBL					Assay Description Inhibition of high affinity uptake by the dopamine transporter from rat synaptosomal nerve endings by using [3H]DA as radioligand				J Med Chem 47: 5821-4 (2004) Article DOI: 10.1021/jm040117o BindingDB Entry DOI: 10.7270/Q2Q81DVF
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50156031 (Acetic acid 2-[4-(4-chloro-phenyl)-1-methyl-piperi...) Show SMILES CN1CCC(C(CS(=O)CCOC(C)=O)C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H24ClNO3S/c1-13(20)22-9-10-23(21)12-15-11-19(2)8-7-17(15)14-3-5-16(18)6-4-14/h3-6,15,17H,7-12H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Acenta Discovery, Inc. Curated by ChEMBL					Assay Description Inhibition of high affinity uptake by the norepinephrine transporter from rat synaptosomal nerve endings by using [3H]NE as radioligand				J Med Chem 47: 5821-4 (2004) Article DOI: 10.1021/jm040117o BindingDB Entry DOI: 10.7270/Q2Q81DVF
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50156031 (Acetic acid 2-[4-(4-chloro-phenyl)-1-methyl-piperi...) Show SMILES CN1CCC(C(CS(=O)CCOC(C)=O)C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H24ClNO3S/c1-13(20)22-9-10-23(21)12-15-11-19(2)8-7-17(15)14-3-5-16(18)6-4-14/h3-6,15,17H,7-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Acenta Discovery, Inc. Curated by ChEMBL					Assay Description Inhibition of high affinity uptake by the serotonin transporter (5-HT) from rat synaptosomal nerve endings by using [3H]5-HT as radioligand				J Med Chem 47: 5821-4 (2004) Article DOI: 10.1021/jm040117o BindingDB Entry DOI: 10.7270/Q2Q81DVF
					More data for this Ligand-Target Pair