BDBM50156298 CHEMBL3781926

SMILES: CC(C)(C)Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1

InChI Key: InChIKey=QEXRIOBQGFISMS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156298 (CHEMBL3781926) Show SMILES CC(C)(C)Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7/c1-21(2,3)28-20-24-13-16(18(27-20)12-14-4-5-14)17-8-11-23-19(26-17)25-15-6-9-22-10-7-15/h6-11,13-14H,4-5,12H2,1-3H3,(H,24,27,28)(H,22,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156298 (CHEMBL3781926) Show SMILES CC(C)(C)Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7/c1-21(2,3)28-20-24-13-16(18(27-20)12-14-4-5-14)17-8-11-23-19(26-17)25-15-6-9-22-10-7-15/h6-11,13-14H,4-5,12H2,1-3H3,(H,24,27,28)(H,22,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair