BDBM50156347 CHEMBL3786898

SMILES: Cn1cc(cn1)-c1ccc2n(CCOc3ccnc4cc(ccc34)-c3cnn(C)c3)c(=O)oc2c1

InChI Key: InChIKey=DNXABYXRZUUHAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50156347 (CHEMBL3786898) Show SMILES Cn1cc(cn1)-c1ccc2n(CCOc3ccnc4cc(ccc34)-c3cnn(C)c3)c(=O)oc2c1 Show InChI InChI=1S/C26H22N6O3/c1-30-15-19(13-28-30)17-3-5-21-22(11-17)27-8-7-24(21)34-10-9-32-23-6-4-18(12-25(23)35-26(32)33)20-14-29-31(2)16-20/h3-8,11-16H,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 115: 191-200 (2016) BindingDB Entry DOI: 10.7270/Q28K7BZ9
					More data for this Ligand-Target Pair