BDBM50156364 CHEMBL3786107
SMILES: Cl.Cl.NC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2nc([nH]c(=O)c2c1)N1CCNCC1
InChI Key: InChIKey=KHNUXTXUBRHINK-TXEPZDRESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50156364![]() (CHEMBL3786107) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of FITC-labelled fibrinogen binding to integrin alpha2b beta3 receptor in human platelet cells | Bioorg Med Chem Lett 26: 1839-43 (2016) BindingDB Entry DOI: 10.7270/Q2NV9M57 | |||||||||||
More data for this Ligand-Target Pair |