BDBM50156767 3-(3-(4-(phenoxymethyl)phenyl)ureido)benzoic acid::CHEMBL224844

SMILES: OC(=O)c1cccc(NC(=O)Nc2ccc(COc3ccccc3)cc2)c1

InChI Key: InChIKey=VTTXQJYYGCSRQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50156767 (3-(3-(4-(phenoxymethyl)phenyl)ureido)benzoic acid ...) Show SMILES OC(=O)c1cccc(NC(=O)Nc2ccc(COc3ccccc3)cc2)c1 Show InChI InChI=1S/C21H18N2O4/c24-20(25)16-5-4-6-18(13-16)23-21(26)22-17-11-9-15(10-12-17)14-27-19-7-2-1-3-8-19/h1-13H,14H2,(H,24,25)(H2,22,23,26)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assay				J Med Chem 47: 6292-8 (2004) Article DOI: 10.1021/jm049933m BindingDB Entry DOI: 10.7270/Q2S1820Z
					More data for this Ligand-Target Pair