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SMILES: COc1cc(NC(=O)c2ccccc2)c(C)cc1NC(=O)CC(CC(O)=O)c1ccccc1

InChI Key: InChIKey=DDBREAJWHLHBKD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156772   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NAD-dependent protein deacetylase sirtuin-2


(Homo sapiens (Human))		BDBM50156772
PNG
(5-(4-benzamido-2-methoxy-5-methylphenylamino)-5-ox...)
Show SMILES COc1cc(NC(=O)c2ccccc2)c(C)cc1NC(=O)CC(CC(O)=O)c1ccccc1
Show InChI InChI=1S/C26H26N2O5/c1-17-13-22(23(33-2)16-21(17)28-26(32)19-11-7-4-8-12-19)27-24(29)14-20(15-25(30)31)18-9-5-3-6-10-18/h3-13,16,20H,14-15H2,1-2H3,(H,27,29)(H,28,32)(H,30,31)
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KEGG

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



University of Kuopio

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assay

J Med Chem 47: 6292-8 (2004)


Article DOI: 10.1021/jm049933m
BindingDB Entry DOI: 10.7270/Q2S1820Z
More data for this
Ligand-Target Pair