BDBM50157313 CHEMBL3786892
SMILES: COc1cc2c(CCC(N)C2(C)C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
InChI Key: InChIKey=WMLFTPJTSQTLNL-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae) | BDBM50157313![]() (CHEMBL3786892) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University Curated by ChEMBL | Assay Description Inhibition of human ERG by patch clamp method | Bioorg Med Chem Lett 26: 1720-5 (2016) BindingDB Entry DOI: 10.7270/Q2TF007P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50157313![]() (CHEMBL3786892) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University Curated by ChEMBL | Assay Description Inhibition of ALK L1196M mutant (unknown origin) after 30 mins by HTRF assay | Bioorg Med Chem Lett 26: 1720-5 (2016) BindingDB Entry DOI: 10.7270/Q2TF007P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50157313![]() (CHEMBL3786892) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University Curated by ChEMBL | Assay Description Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assay | Bioorg Med Chem Lett 26: 1720-5 (2016) BindingDB Entry DOI: 10.7270/Q2TF007P | |||||||||||
More data for this Ligand-Target Pair |