BDBM50157338 4-(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxymethyl)-3,4,5,6-tetrahydro-2H-[1,4'']bipyridinyl-3''-carboxylic acid methyl ester; di hydrochloride::4-(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxymethyl)-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-carboxylic acid methyl ester; dihydrochloride::CHEMBL535369

SMILES: COC(=O)c1cnccc1N1CCC(COc2ccc3CCN(Cc3c2)C(N)=N)CC1

InChI Key: InChIKey=GCIUXKVYTBFLAH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50157338 (4-(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-...) Show SMILES COC(=O)c1cnccc1N1CCC(COc2ccc3CCN(Cc3c2)C(N)=N)CC1 Show InChI InChI=1S/C23H29N5O3/c1-30-22(29)20-13-26-8-4-21(20)27-9-5-16(6-10-27)15-31-19-3-2-17-7-11-28(23(24)25)14-18(17)12-19/h2-4,8,12-13,16H,5-7,9-11,14-15H2,1H3,(H3,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				J Med Chem 48: 3586-604 (2005) Article DOI: 10.1021/jm058160e BindingDB Entry DOI: 10.7270/Q2CR5V36
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50157338 (4-(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-...) Show SMILES COC(=O)c1cnccc1N1CCC(COc2ccc3CCN(Cc3c2)C(N)=N)CC1 Show InChI InChI=1S/C23H29N5O3/c1-30-22(29)20-13-26-8-4-21(20)27-9-5-16(6-10-27)15-31-19-3-2-17-7-11-28(23(24)25)14-18(17)12-19/h2-4,8,12-13,16H,5-7,9-11,14-15H2,1H3,(H3,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor II (thrombin)				J Med Chem 48: 3586-604 (2005) Article DOI: 10.1021/jm058160e BindingDB Entry DOI: 10.7270/Q2CR5V36
					More data for this Ligand-Target Pair