BDBM50157767 CHEMBL376662::N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-4-(2-methoxyphenyl)-1-piperazinebutanamide

SMILES: COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC

InChI Key: InChIKey=LRBVYKFKCTTYEH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50157767 (CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...) Show SMILES COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)27-26(30)14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cells				J Med Chem 47: 6616-24 (2004) Article DOI: 10.1021/jm049702f BindingDB Entry DOI: 10.7270/Q2RX9BKX
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50157767 (CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...) Show SMILES COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)27-26(30)14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50157767 (CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...) Show SMILES COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)27-26(30)14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		254	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50157767 (CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...) Show SMILES COc1cccc2C(CCCc12)NC(=O)CCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)27-26(30)14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	254	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Wistar Han rat hippocampal membranes				J Med Chem 47: 6616-24 (2004) Article DOI: 10.1021/jm049702f BindingDB Entry DOI: 10.7270/Q2RX9BKX
					More data for this Ligand-Target Pair