BDBM50158405 CHEMBL3785800

SMILES: Cc1ccc2n(CCOc3ccnc4cc(OCCCCN5CCOCC5)ccc34)c(=O)oc2c1

InChI Key: InChIKey=RNSVKOARMXUAGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50158405 (CHEMBL3785800) Show SMILES Cc1ccc2n(CCOc3ccnc4cc(OCCCCN5CCOCC5)ccc34)c(=O)oc2c1 Show InChI InChI=1S/C27H31N3O5/c1-20-4-7-24-26(18-20)35-27(31)30(24)13-17-34-25-8-9-28-23-19-21(5-6-22(23)25)33-14-3-2-10-29-11-15-32-16-12-29/h4-9,18-19H,2-3,10-17H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 115: 191-200 (2016) BindingDB Entry DOI: 10.7270/Q28K7BZ9
					More data for this Ligand-Target Pair