BDBM50158545 CHEMBL3780482

SMILES: Cc1ccc(cc1O)N1CC(=O)C(=C1N)c1nc2ccccc2[nH]1

InChI Key: InChIKey=WPHODUIPGOZTOR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50158545 (CHEMBL3780482) Show SMILES Cc1ccc(cc1O)N1CC(=O)C(=C1N)c1nc2ccccc2[nH]1 |c:13| Show InChI InChI=1S/C18H16N4O2/c1-10-6-7-11(8-14(10)23)22-9-15(24)16(17(22)19)18-20-12-4-2-3-5-13(12)21-18/h2-8,23H,9,19H2,1H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 residues) expressed in baculovirus infected insect Sf21 cells after 25 mins u...				Bioorg Med Chem 24: 2053-9 (2016) BindingDB Entry DOI: 10.7270/Q2D50PVJ
					More data for this Ligand-Target Pair