BDBM50158553 3-{2-[3-(3-bromophenyl)ureido]-4-chlorophenyl}-propionic acid::CHEMBL224837

SMILES: OC(=O)CCc1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1

InChI Key: InChIKey=CQFFISLLTAUFJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIK1 (Homo sapiens (Human))	BDBM50158553 (3-{2-[3-(3-bromophenyl)ureido]-4-chlorophenyl}-pro...) Show SMILES OC(=O)CCc1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C16H14BrClN2O3/c17-11-2-1-3-13(8-11)19-16(23)20-14-9-12(18)6-4-10(14)5-7-15(21)22/h1-4,6,8-9H,5,7H2,(H,21,22)(H2,19,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at human homomeric GluR5 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assay				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair