BDBM50158556 1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-phenyl]urea::CHEMBL224926

SMILES: Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1

InChI Key: InChIKey=KPIUSQVXLDOKOG-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50158556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR1 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at human homomeric GluR5 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assay				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Displacement of [3HATPA from human recombinant GluR5				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at human homomeric GluR6 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assay				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR3 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair