BDBM50158611 (4-Methoxy-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-methanone::CHEMBL178410

SMILES: COc1ccc(cc1)C(=O)c1ccc2oc(CCN3CCC[C@H]3C)cc2c1

InChI Key: InChIKey=ZGSUVVWUSJSBAJ-MRXNPFEDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50158611 ((4-Methoxy-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-...) Show SMILES COc1ccc(cc1)C(=O)c1ccc2oc(CCN3CCC[C@H]3C)cc2c1 Show InChI InChI=1S/C23H25NO3/c1-16-4-3-12-24(16)13-11-21-15-19-14-18(7-10-22(19)27-21)23(25)17-5-8-20(26-2)9-6-17/h5-10,14-16H,3-4,11-13H2,1-2H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor				J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50158611 ((4-Methoxy-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-...) Show SMILES COc1ccc(cc1)C(=O)c1ccc2oc(CCN3CCC[C@H]3C)cc2c1 Show InChI InChI=1S/C23H25NO3/c1-16-4-3-12-24(16)13-11-21-15-19-14-18(7-10-22(19)27-21)23(25)17-5-8-20(26-2)9-6-17/h5-10,14-16H,3-4,11-13H2,1-2H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing rat histamine H3 receptor				J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST
					More data for this Ligand-Target Pair