null

SMILES: CC1(O)CCN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccccc3)cc2)C1

InChI Key: InChIKey=ZJUPVLQHLOIMEV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50159145 (CHEMBL3786685) Show SMILES CC1(O)CCN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccccc3)cc2)C1 Show InChI InChI=1S/C24H26N4O4/c1-24(30)11-12-27(16-24)13-17-7-9-19(10-8-17)31-20-14-28(15-20)23(29)22-26-25-21(32-22)18-5-3-2-4-6-18/h2-10,20,30H,11-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50159145 (CHEMBL3786685) Show SMILES CC1(O)CCN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccccc3)cc2)C1 Show InChI InChI=1S/C24H26N4O4/c1-24(30)11-12-27(16-24)13-17-7-9-19(10-8-17)31-20-14-28(15-20)23(29)22-26-25-21(32-22)18-5-3-2-4-6-18/h2-10,20,30H,11-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50159145 (CHEMBL3786685) Show SMILES CC1(O)CCN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccccc3)cc2)C1 Show InChI InChI=1S/C24H26N4O4/c1-24(30)11-12-27(16-24)13-17-7-9-19(10-8-17)31-20-14-28(15-20)23(29)22-26-25-21(32-22)18-5-3-2-4-6-18/h2-10,20,30H,11-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG by IonWork assay				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair