BDBM50159505 CHEMBL1779158::N,N-Dibenzyltryptamine

SMILES: C(Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1

InChI Key: InChIKey=WEWPMAKQEUSKPV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (TRPM8) (Rattus norvegicus (Rat))	BDBM50159505 (CHEMBL1779158 | N,N-Dibenzyltryptamine) Show SMILES C(Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H24N2/c1-3-9-20(10-4-1)18-26(19-21-11-5-2-6-12-21)16-15-22-17-25-24-14-8-7-13-23(22)24/h1-14,17,25H,15-16,18-19H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-d...				J Med Chem 61: 6140-6152 (2018) Article DOI: 10.1021/acs.jmedchem.8b00545 BindingDB Entry DOI: 10.7270/Q2FN18V3
					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (TRPM8) (Rattus norvegicus (Rat))	BDBM50159505 (CHEMBL1779158 | N,N-Dibenzyltryptamine) Show SMILES C(Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H24N2/c1-3-9-20(10-4-1)18-26(19-21-11-5-2-6-12-21)16-15-22-17-25-24-14-8-7-13-23(22)24/h1-14,17,25H,15-16,18-19H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	367	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at +80 mV holding potential b...				J Med Chem 59: 2179-91 (2016) BindingDB Entry DOI: 10.7270/Q2B85B1Z
					More data for this Ligand-Target Pair