BDBM50160199 6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ol::CHEMBL182020

SMILES: Fc1ccc(cc1)-c1nc2nc[nH]c(=O)c2nc1-c1ccc(F)cc1

InChI Key: InChIKey=ANUYUHYVAXDKID-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nonstructural protein 5A (Hepatitis C virus)	BDBM50160199 (6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ol | CHEMBL18...) Show SMILES Fc1ccc(cc1)-c1nc2nc[nH]c(=O)c2nc1-c1ccc(F)cc1 Show InChI InChI=1S/C18H10F2N4O/c19-12-5-1-10(2-6-12)14-15(11-3-7-13(20)8-4-11)24-17-16(23-14)18(25)22-9-21-17/h1-9H,(H,21,22,24,25)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Y181C reverse transcriptase.				Eur J Med Chem 164: 576-601 (2019) Article DOI: 10.1007/s00044-005-0131-1 BindingDB Entry DOI: 10.7270/Q2RR224D
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50160199 (6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ol | CHEMBL18...) Show SMILES Fc1ccc(cc1)-c1nc2nc[nH]c(=O)c2nc1-c1ccc(F)cc1 Show InChI InChI=1S/C18H10F2N4O/c19-12-5-1-10(2-6-12)14-15(11-3-7-13(20)8-4-11)24-17-16(23-14)18(25)22-9-21-17/h1-9H,(H,21,22,24,25)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Valeant Pharmaceuticals International Curated by ChEMBL					Assay Description Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of hepatitis C virus				Bioorg Med Chem Lett 15: 675-8 (2005) Article DOI: 10.1016/j.bmcl.2004.11.028 BindingDB Entry DOI: 10.7270/Q2J38S22
					More data for this Ligand-Target Pair