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SMILES: COc1cc2[nH]c(=S)n(-c3cccnc3)c(=O)c2cc1-c1cnco1

InChI Key: InChIKey=UOKUVPKDXLNWDQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160376   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50160376
PNG
(7-Methoxy-6-oxazol-5-yl-3-pyridin-3-yl-2-thioxo-2,...)
Show SMILES COc1cc2[nH]c(=S)n(-c3cccnc3)c(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C17H12N4O3S/c1-23-14-6-13-11(5-12(14)15-8-19-9-24-15)16(22)21(17(25)20-13)10-3-2-4-18-7-10/h2-9H,1H3,(H,20,25)
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MMDB

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n/an/a 1.71E+3n/an/an/an/an/an/a



Celltech R and D

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenase

Bioorg Med Chem Lett 15: 751-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.015
BindingDB Entry DOI: 10.7270/Q2RN37CZ
More data for this
Ligand-Target Pair