BDBM50160854 1-[4-(4-Methoxy-pyridin-3-yloxy)-phenyl]-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL361533

SMILES: COc1ccncc1Oc1ccc(cc1)N1C(=O)CCC11C(=O)NC(=O)NC1=O

InChI Key: InChIKey=ABVSHXSHGCSUFR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50160854 (1-[4-(4-Methoxy-pyridin-3-yloxy)-phenyl]-1,7,9-tri...) Show SMILES COc1ccncc1Oc1ccc(cc1)N1C(=O)CCC11C(=O)NC(=O)NC1=O Show InChI InChI=1S/C19H16N4O6/c1-28-13-7-9-20-10-14(13)29-12-4-2-11(3-5-12)23-15(24)6-8-19(23)16(25)21-18(27)22-17(19)26/h2-5,7,9-10H,6,8H2,1H3,(H2,21,22,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 15: 1101-6 (2005) Article DOI: 10.1016/j.bmcl.2004.12.016 BindingDB Entry DOI: 10.7270/Q2F47NN2
					More data for this Ligand-Target Pair