BDBM50160919 (6S,7aS)-6-[(4''-Bromo-biphenyl-3-ylmethyl)-methyl-amino]-2-(3,5-dichloro-phenyl)-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL361737

SMILES: CN(Cc1cccc(c1)-c1ccc(Br)cc1)[C@H]1Cc2c(O)n(-c3cc(Cl)cc(Cl)c3)c(=O)n2C1

InChI Key: InChIKey=ZKHIBSNIRIACQF-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160919 ((6S,7aS)-6-[(4''-Bromo-biphenyl-3-ylmethyl)-methyl...) Show SMILES CN(Cc1cccc(c1)-c1ccc(Br)cc1)[C@H]1Cc2c(O)n(-c3cc(Cl)cc(Cl)c3)c(=O)n2C1 Show InChI InChI=1S/C26H22BrCl2N3O2/c1-30(14-16-3-2-4-18(9-16)17-5-7-19(27)8-6-17)23-13-24-25(33)32(26(34)31(24)15-23)22-11-20(28)10-21(29)12-22/h2-12,23,33H,13-15H2,1H3/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
					More data for this Ligand-Target Pair