BDBM50161621 (1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine::6-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL362073

SMILES: CC1CNCCc2c(Cl)cccc12

InChI Key: InChIKey=HMGASYPJYKHVCW-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50161621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50161621 ((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...) Show SMILES CC1CNCCc2c(Cl)cccc12 Show InChI InChI=1S/C11H14ClN/c1-8-7-13-6-5-10-9(8)3-2-4-11(10)12/h2-4,8,13H,5-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...				Bioorg Med Chem Lett 15: 1467-70 (2005) Article DOI: 10.1016/j.bmcl.2004.12.080 BindingDB Entry DOI: 10.7270/Q21R6Q0G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50161621 ((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...) Show SMILES CC1CNCCc2c(Cl)cccc12 Show InChI InChI=1S/C11H14ClN/c1-8-7-13-6-5-10-9(8)3-2-4-11(10)12/h2-4,8,13H,5-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration towards 5-hydroxytryptamine 2A receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...				Bioorg Med Chem Lett 15: 1467-70 (2005) Article DOI: 10.1016/j.bmcl.2004.12.080 BindingDB Entry DOI: 10.7270/Q21R6Q0G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50161621 ((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...) Show SMILES CC1CNCCc2c(Cl)cccc12 Show InChI InChI=1S/C11H14ClN/c1-8-7-13-6-5-10-9(8)3-2-4-11(10)12/h2-4,8,13H,5-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as intracellular IP3 accumulation				J Med Chem 51: 305-13 (2008) Article DOI: 10.1021/jm0709034 BindingDB Entry DOI: 10.7270/Q26Q211B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50161621 ((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...) Show SMILES CC1CNCCc2c(Cl)cccc12 Show InChI InChI=1S/C11H14ClN/c1-8-7-13-6-5-10-9(8)3-2-4-11(10)12/h2-4,8,13H,5-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as intracellular IP3 accumulation				J Med Chem 51: 305-13 (2008) Article DOI: 10.1021/jm0709034 BindingDB Entry DOI: 10.7270/Q26Q211B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50161621 ((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...) Show SMILES CC1CNCCc2c(Cl)cccc12 Show InChI InChI=1S/C11H14ClN/c1-8-7-13-6-5-10-9(8)3-2-4-11(10)12/h2-4,8,13H,5-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as intracellular IP3 accumulation				J Med Chem 51: 305-13 (2008) Article DOI: 10.1021/jm0709034 BindingDB Entry DOI: 10.7270/Q26Q211B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50161621 ((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...) Show SMILES CC1CNCCc2c(Cl)cccc12 Show InChI InChI=1S/C11H14ClN/c1-8-7-13-6-5-10-9(8)3-2-4-11(10)12/h2-4,8,13H,5-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...				Bioorg Med Chem Lett 15: 1467-70 (2005) Article DOI: 10.1016/j.bmcl.2004.12.080 BindingDB Entry DOI: 10.7270/Q21R6Q0G
					More data for this Ligand-Target Pair