BDBM50161632 7-Bromo-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL180166

SMILES: COc1cc2CCNCCc2cc1Br

InChI Key: InChIKey=GDBBQVJRKVPDDA-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50161632 (7-Bromo-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]az...) Show SMILES COc1cc2CCNCCc2cc1Br Show InChI InChI=1S/C11H14BrNO/c1-14-11-7-9-3-5-13-4-2-8(9)6-10(11)12/h6-7,13H,2-5H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...				Bioorg Med Chem Lett 15: 1467-70 (2005) Article DOI: 10.1016/j.bmcl.2004.12.080 BindingDB Entry DOI: 10.7270/Q21R6Q0G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50161632 (7-Bromo-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]az...) Show SMILES COc1cc2CCNCCc2cc1Br Show InChI InChI=1S/C11H14BrNO/c1-14-11-7-9-3-5-13-4-2-8(9)6-10(11)12/h6-7,13H,2-5H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...				Bioorg Med Chem Lett 15: 1467-70 (2005) Article DOI: 10.1016/j.bmcl.2004.12.080 BindingDB Entry DOI: 10.7270/Q21R6Q0G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50161632 (7-Bromo-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]az...) Show SMILES COc1cc2CCNCCc2cc1Br Show InChI InChI=1S/C11H14BrNO/c1-14-11-7-9-3-5-13-4-2-8(9)6-10(11)12/h6-7,13H,2-5H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration towards 5-hydroxytryptamine 2A receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...				Bioorg Med Chem Lett 15: 1467-70 (2005) Article DOI: 10.1016/j.bmcl.2004.12.080 BindingDB Entry DOI: 10.7270/Q21R6Q0G
					More data for this Ligand-Target Pair