BDBM50162010 3-((R)-2-Amino-2-phenyl-ethyl)-1-(3-fluoro-benzyl)-5-(2-fluoro-phenyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL179663

SMILES: Cc1c(-c2ccccc2F)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1cccc(F)c1

InChI Key: InChIKey=SEYOJLYQIAAVHG-QHCPKHFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50162010 (3-((R)-2-Amino-2-phenyl-ethyl)-1-(3-fluoro-benzyl)...) Show SMILES Cc1c(-c2ccccc2F)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1cccc(F)c1 |wD:14.15,(4,-1.38,;2.64,-.61,;2.64,.93,;4,1.72,;5.3,.93,;6.66,1.7,;6.66,3.24,;5.3,4.01,;3.97,3.24,;2.64,4.01,;1.31,1.72,;1.31,3.26,;.01,.93,;-1.35,1.72,;-2.68,.93,;-2.68,-.61,;-4.01,1.7,;-4.01,3.24,;-5.34,4.01,;-6.67,3.24,;-6.67,1.68,;-5.34,.93,;.01,-.61,;-1.35,-1.38,;1.31,-1.36,;1.31,-2.9,;-.02,-3.67,;-1.35,-2.89,;-2.68,-3.66,;-2.68,-5.2,;-1.32,-5.97,;-1.32,-7.51,;.01,-5.2,)| Show InChI InChI=1S/C26H23F2N3O2/c1-17-24(21-12-5-6-13-22(21)28)25(32)31(16-23(29)19-9-3-2-4-10-19)26(33)30(17)15-18-8-7-11-20(27)14-18/h2-14,23H,15-16,29H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for Human gonadotropin-releasing hormone receptor				J Med Chem 48: 1169-78 (2005) Article DOI: 10.1021/jm049218c BindingDB Entry DOI: 10.7270/Q2MK6CD8
					More data for this Ligand-Target Pair