BDBM50162097 3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(4-methoxy-phenyl)-1H-indole-6-carboxylic acid::CHEMBL179970

SMILES: COc1ccc(cc1)-c1c(C2CCCCC2)c2ccc(cc2n1CC(=O)N(C)C)C(O)=O

InChI Key: InChIKey=APYFPTCHPWHPPR-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50162097 (3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(4-methox...) Show SMILES COc1ccc(cc1)-c1c(C2CCCCC2)c2ccc(cc2n1CC(=O)N(C)C)C(O)=O Show InChI InChI=1S/C26H30N2O4/c1-27(2)23(29)16-28-22-15-19(26(30)31)11-14-21(22)24(17-7-5-4-6-8-17)25(28)18-9-12-20(32-3)13-10-18/h9-15,17H,4-8,16H2,1-3H3,(H,30,31)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
IRBM (Merck Research Laboratories Rome) Curated by ChEMBL					Assay Description Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1				J Med Chem 48: 1314-7 (2005) Article DOI: 10.1021/jm049122i BindingDB Entry DOI: 10.7270/Q2C24VXP
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50162097 (3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(4-methox...) Show SMILES COc1ccc(cc1)-c1c(C2CCCCC2)c2ccc(cc2n1CC(=O)N(C)C)C(O)=O Show InChI InChI=1S/C26H30N2O4/c1-27(2)23(29)16-28-22-15-19(26(30)31)11-14-21(22)24(17-7-5-4-6-8-17)25(28)18-9-12-20(32-3)13-10-18/h9-15,17H,4-8,16H2,1-3H3,(H,30,31)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
IRBM (Merck Research Laboratories Rome) Curated by ChEMBL					Assay Description Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1				J Med Chem 48: 1314-7 (2005) Article DOI: 10.1021/jm049122i BindingDB Entry DOI: 10.7270/Q2C24VXP
					More data for this Ligand-Target Pair