BDBM50162111 2-(2-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamoylmethyl-1H-indole-6-carboxylic acid::CHEMBL369552

SMILES: CN(C)C(=O)Cn1c(c(C2CCCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1Cl

InChI Key: InChIKey=YRKLWUFLMYGEPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50162111 (2-(2-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...) Show SMILES CN(C)C(=O)Cn1c(c(C2CCCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1Cl |(-.96,6.24,;.05,5.1,;1.57,5.4,;-.41,3.65,;-1.93,3.33,;.61,2.49,;.12,1.04,;1.03,-.22,;.12,-1.45,;.52,-2.95,;-.55,-4.04,;-.16,-5.51,;1.34,-5.91,;2.43,-4.81,;2.01,-3.32,;-1.34,-.99,;-2.67,-1.76,;-4,-.99,;-4,.55,;-2.67,1.32,;-1.34,.55,;-5.36,1.32,;-6.69,.55,;-5.36,2.86,;2.57,-.05,;3.2,1.34,;4.74,1.49,;5.64,.23,;5,-1.19,;3.46,-1.31,;2.83,-2.71,)| Show InChI InChI=1S/C25H27ClN2O3/c1-27(2)22(29)15-28-21-14-17(25(30)31)12-13-19(21)23(16-8-4-3-5-9-16)24(28)18-10-6-7-11-20(18)26/h6-7,10-14,16H,3-5,8-9,15H2,1-2H3,(H,30,31)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	372	n/a	n/a	n/a	n/a	n/a	n/a
IRBM (Merck Research Laboratories Rome) Curated by ChEMBL					Assay Description Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1				J Med Chem 48: 1314-7 (2005) Article DOI: 10.1021/jm049122i BindingDB Entry DOI: 10.7270/Q2C24VXP
					More data for this Ligand-Target Pair