BDBM50163418 2-Furan-2-yl-N*5*-[1-(5-methyl-isoxazol-3-ylmethyl)-piperidin-4-yl]-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine::CHEMBL368092

SMILES: Cc1cc(CN2CCC(CC2)Nc2nc(N)n3nc(nc3n2)-c2ccco2)no1

InChI Key: InChIKey=ACTNRWABPDYOKF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50163418 (2-Furan-2-yl-N*5*-[1-(5-methyl-isoxazol-3-ylmethyl...) Show SMILES Cc1cc(CN2CCC(CC2)Nc2nc(N)n3nc(nc3n2)-c2ccco2)no1 Show InChI InChI=1S/C18H21N9O2/c1-11-9-13(25-29-11)10-26-6-4-12(5-7-26)20-17-22-16(19)27-18(23-17)21-15(24-27)14-3-2-8-28-14/h2-3,8-9,12H,4-7,10H2,1H3,(H3,19,20,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]ZM-241385 binding to adenosine A2a receptor of rat brain tissue				J Med Chem 48: 2009-18 (2005) Article DOI: 10.1021/jm0498396 BindingDB Entry DOI: 10.7270/Q2NZ88FB
					More data for this Ligand-Target Pair