BDBM50163728 (Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-amino)-acetic acid::2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)(benzyl)amino)acetic acid::CHEMBL371120

SMILES: Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1

InChI Key: InChIKey=KBXHBLXYBPVCLB-UHFFFAOYSA-N

Data: 4 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Effective concentration against human Peroxisome proliferator activated receptor gamma				J Med Chem 48: 2248-50 (2005) Article DOI: 10.1021/jm0496436 BindingDB Entry DOI: 10.7270/Q2SX6CRR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Peroxisome proliferator activated receptor gamma				J Med Chem 48: 2248-50 (2005) Article DOI: 10.1021/jm0496436 BindingDB Entry DOI: 10.7270/Q2SX6CRR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Peroxisome proliferator activated receptor alpha				J Med Chem 48: 2248-50 (2005) Article DOI: 10.1021/jm0496436 BindingDB Entry DOI: 10.7270/Q2SX6CRR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.02E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Agonist activity at PPARalpha receptor expressed in HEK293 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 2312-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.060 BindingDB Entry DOI: 10.7270/Q21N80ST
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of fluorescein labeled ligand from PPARgamma receptor by fluorescence polarization assay				Bioorg Med Chem Lett 17: 2312-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.060 BindingDB Entry DOI: 10.7270/Q21N80ST
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of fluorescein labeled ligand from PPARalpha receptor by fluorescence polarization assay				Bioorg Med Chem Lett 17: 2312-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.060 BindingDB Entry DOI: 10.7270/Q21N80ST
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 2312-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.060 BindingDB Entry DOI: 10.7270/Q21N80ST
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50163728 ((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...) Show SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1 Show InChI InChI=1S/C28H28N2O4/c1-21-26(29-28(34-21)24-10-6-3-7-11-24)16-17-33-25-14-12-23(13-15-25)19-30(20-27(31)32)18-22-8-4-2-5-9-22/h2-15H,16-20H2,1H3,(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Effective concentration against human Peroxisome proliferator activated receptor alpha				J Med Chem 48: 2248-50 (2005) Article DOI: 10.1021/jm0496436 BindingDB Entry DOI: 10.7270/Q2SX6CRR
					More data for this Ligand-Target Pair