BDBM50164355 6-(4-Chloro-phenyl)-3-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL189437

SMILES: COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=MOIUZUKSUMOMKZ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50164355 (6-(4-Chloro-phenyl)-3-{2-[4-(2-methoxy-phenyl)-pip...) Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H26ClN5O3/c1-34-22-5-3-2-4-21(22)30-13-10-29(11-14-30)12-15-31-24(32)23-20(28-25(31)33)16-19(27-23)17-6-8-18(26)9-7-17/h2-9,16,27H,10-15H2,1H3,(H,28,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description Inhibition of [3H]-spiperone binding to Dopamine receptor D2 from rat striatum				J Med Chem 48: 2420-31 (2005) Article DOI: 10.1021/jm040870h BindingDB Entry DOI: 10.7270/Q2377872
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164355 (6-(4-Chloro-phenyl)-3-{2-[4-(2-methoxy-phenyl)-pip...) Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H26ClN5O3/c1-34-22-5-3-2-4-21(22)30-13-10-29(11-14-30)12-15-31-24(32)23-20(28-25(31)33)16-19(27-23)17-6-8-18(26)9-7-17/h2-9,16,27H,10-15H2,1H3,(H,28,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Catania Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry				Bioorg Med Chem 19: 5260-76 (2011) Article DOI: 10.1016/j.bmc.2011.06.043 BindingDB Entry DOI: 10.7270/Q2D50NBD
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50164355 (6-(4-Chloro-phenyl)-3-{2-[4-(2-methoxy-phenyl)-pip...) Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H26ClN5O3/c1-34-22-5-3-2-4-21(22)30-13-10-29(11-14-30)12-15-31-24(32)23-20(28-25(31)33)16-19(27-23)17-6-8-18(26)9-7-17/h2-9,16,27H,10-15H2,1H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description Inhibition of [3H]-SCH-23,390 binding to Dopamine receptor D1 from rat striatum				J Med Chem 48: 2420-31 (2005) Article DOI: 10.1021/jm040870h BindingDB Entry DOI: 10.7270/Q2377872
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164355 (6-(4-Chloro-phenyl)-3-{2-[4-(2-methoxy-phenyl)-pip...) Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H26ClN5O3/c1-34-22-5-3-2-4-21(22)30-13-10-29(11-14-30)12-15-31-24(32)23-20(28-25(31)33)16-19(27-23)17-6-8-18(26)9-7-17/h2-9,16,27H,10-15H2,1H3,(H,28,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description Inhibtion of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from rat hippocampus				J Med Chem 48: 2420-31 (2005) Article DOI: 10.1021/jm040870h BindingDB Entry DOI: 10.7270/Q2377872
					More data for this Ligand-Target Pair