null

SMILES: COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@H](N)Cc2c[nH]c3ccccc23)cc1

InChI Key: InChIKey=MQLCJXCOIKRMFV-POURPWNDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50165604 (CHEMBL3798204) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@H](N)Cc2c[nH]c3ccccc23)cc1 |r| Show InChI InChI=1S/C34H38N8O2/c1-34(2,36)33(43)39-30(17-23-19-38-29-11-7-5-9-26(23)29)32-41-40-31(42(32)20-21-12-14-24(44-3)15-13-21)27(35)16-22-18-37-28-10-6-4-8-25(22)28/h4-15,18-19,27,30,37-38H,16-17,20,35-36H2,1-3H3,(H,39,43)/t27-,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Displacement of [125I]-His9-ghrelin from human GHS-R1a transfected in pig LLC PK-1 cell membranes after 60 mins by gamma counting method				Bioorg Med Chem Lett 26: 2408-12 (2016) Article DOI: 10.1016/j.bmcl.2016.04.003 BindingDB Entry DOI: 10.7270/Q2J9688V
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50165604 (CHEMBL3798204) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@H](N)Cc2c[nH]c3ccccc23)cc1 |r| Show InChI InChI=1S/C34H38N8O2/c1-34(2,36)33(43)39-30(17-23-19-38-29-11-7-5-9-26(23)29)32-41-40-31(42(32)20-21-12-14-24(44-3)15-13-21)27(35)16-22-18-37-28-10-6-4-8-25(22)28/h4-15,18-19,27,30,37-38H,16-17,20,35-36H2,1-3H3,(H,39,43)/t27-,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...				Bioorg Med Chem Lett 26: 2408-12 (2016) Article DOI: 10.1016/j.bmcl.2016.04.003 BindingDB Entry DOI: 10.7270/Q2J9688V
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50165604 (CHEMBL3798204) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@H](N)Cc2c[nH]c3ccccc23)cc1 |r| Show InChI InChI=1S/C34H38N8O2/c1-34(2,36)33(43)39-30(17-23-19-38-29-11-7-5-9-26(23)29)32-41-40-31(42(32)20-21-12-14-24(44-3)15-13-21)27(35)16-22-18-37-28-10-6-4-8-25(22)28/h4-15,18-19,27,30,37-38H,16-17,20,35-36H2,1-3H3,(H,39,43)/t27-,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...				Bioorg Med Chem Lett 26: 2408-12 (2016) Article DOI: 10.1016/j.bmcl.2016.04.003 BindingDB Entry DOI: 10.7270/Q2J9688V
					More data for this Ligand-Target Pair