BDBM50165711 CHEMBL3798126

SMILES: CCC[C@H]1N(CCC[C@@]1(Oc1ccc(cc1)C(F)(F)F)C(=O)N1CCC(CC1)Oc1cccc(Cl)n1)C(=O)c1cnccc1C(F)(F)F

InChI Key: InChIKey=GPVPCAJHVQMJBI-YOYKQTLTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM50165711 (CHEMBL3798126) Show SMILES CCC[C@H]1N(CCC[C@@]1(Oc1ccc(cc1)C(F)(F)F)C(=O)N1CCC(CC1)Oc1cccc(Cl)n1)C(=O)c1cnccc1C(F)(F)F |r| Show InChI InChI=1S/C13H16BrNO6/c14-8-3-1-7(2-4-8)5-15-21-13-12(19)11(18)10(17)9(6-16)20-13/h1-5,9-13,16-19H,6H2/b15-5+/t9?,10?,11-,12?,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MDM2 assessed as inhibition of interaction with p53 by fluorescence polarization assay				Bioorg Med Chem Lett 26: 2735-8 (2016) Article DOI: 10.1016/j.bmcl.2016.03.078 BindingDB Entry DOI: 10.7270/Q28S4RTD
					More data for this Ligand-Target Pair