BDBM50165890 CHEMBL3798102

SMILES: COc1cc2ncnc(Nc3cccc4[nH]cnc34)c2cc1OC

InChI Key: InChIKey=CZHWCGQVANVYIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50165890 (CHEMBL3798102) Show SMILES COc1cc2ncnc(Nc3cccc4[nH]cnc34)c2cc1OC Show InChI InChI=1S/C17H15N5O2/c1-23-14-6-10-13(7-15(14)24-2)19-9-21-17(10)22-12-5-3-4-11-16(12)20-8-18-11/h3-9H,1-2H3,(H,18,20)(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal GST fused human RET (658 to 1114 amino acid residue) using CSKtide as substrate expressed in baculovirus preincubated for 15...				Bioorg Med Chem Lett 26: 2724-9 (2016) Article DOI: 10.1016/j.bmcl.2016.03.100 BindingDB Entry DOI: 10.7270/Q2WM1G93
					More data for this Ligand-Target Pair