BDBM50166232 (2R,3S,4R,5R)-2-Hydroxymethyl-5-(6-phenylamino-8-vinyl-purin-9-yl)-tetrahydro-furan-3,4-diol::CHEMBL189106

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c(C=C)nc2c(Nc3ccccc3)ncnc12

InChI Key: InChIKey=LUFONISLOJXURL-XKLVTHTNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine kinase (Homo sapiens (Human))	BDBM50166232 ((2R,3S,4R,5R)-2-Hydroxymethyl-5-(6-phenylamino-8-v...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c(C=C)nc2c(Nc3ccccc3)ncnc12 Show InChI InChI=1S/C18H19N5O4/c1-2-12-22-13-16(21-10-6-4-3-5-7-10)19-9-20-17(13)23(12)18-15(26)14(25)11(8-24)27-18/h2-7,9,11,14-15,18,24-26H,1,8H2,(H,19,20,21)/t11-,14-,15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Human Recombinant Adenosine Kinase				J Med Chem 48: 3389-99 (2005) Article DOI: 10.1021/jm048968j BindingDB Entry DOI: 10.7270/Q2RR1XRF
					More data for this Ligand-Target Pair