BDBM50167019 4-(7-Carbamimidoyl-naphthalene-2-sulfonylamino)-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid; dihydrochloride::CHEMBL537637

SMILES: NC(=N)N1CCc2ccc(cc2C1)S(=O)(=O)NC1(CCN(CC1)c1ccncc1)C(O)=O

InChI Key: InChIKey=QASUVWNUUZGVCY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50167019 (4-(7-Carbamimidoyl-naphthalene-2-sulfonylamino)-3,...) Show SMILES NC(=N)N1CCc2ccc(cc2C1)S(=O)(=O)NC1(CCN(CC1)c1ccncc1)C(O)=O Show InChI InChI=1S/C21H26N6O4S/c22-20(23)27-10-5-15-1-2-18(13-16(15)14-27)32(30,31)25-21(19(28)29)6-11-26(12-7-21)17-3-8-24-9-4-17/h1-4,8-9,13,25H,5-7,10-12,14H2,(H3,22,23)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				J Med Chem 48: 3586-604 (2005) Article DOI: 10.1021/jm058160e BindingDB Entry DOI: 10.7270/Q2CR5V36
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50167019 (4-(7-Carbamimidoyl-naphthalene-2-sulfonylamino)-3,...) Show SMILES NC(=N)N1CCc2ccc(cc2C1)S(=O)(=O)NC1(CCN(CC1)c1ccncc1)C(O)=O Show InChI InChI=1S/C21H26N6O4S/c22-20(23)27-10-5-15-1-2-18(13-16(15)14-27)32(30,31)25-21(19(28)29)6-11-26(12-7-21)17-3-8-24-9-4-17/h1-4,8-9,13,25H,5-7,10-12,14H2,(H3,22,23)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor II (thrombin)				J Med Chem 48: 3586-604 (2005) Article DOI: 10.1021/jm058160e BindingDB Entry DOI: 10.7270/Q2CR5V36
					More data for this Ligand-Target Pair