BDBM50167304 (1S)-2-cyclohexyl-1-methylethyl 2-tert-butyl-2-cyanohydrazinecarboxylate::CHEMBL192604

SMILES: C[C@@H](CC1CCCCC1)OC(=O)NN(C#N)C(C)(C)C

InChI Key: InChIKey=QPRYSWVNTFKRJF-LBPRGKRZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50167304 ((1S)-2-cyclohexyl-1-methylethyl 2-tert-butyl-2-cya...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)NN(C#N)C(C)(C)C Show InChI InChI=1S/C15H27N3O2/c1-12(10-13-8-6-5-7-9-13)20-14(19)17-18(11-16)15(2,3)4/h12-13H,5-10H2,1-4H3,(H,17,19)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 3039-43 (2005) Article DOI: 10.1016/j.bmcl.2005.04.032 BindingDB Entry DOI: 10.7270/Q2MS3S8C
					More data for this Ligand-Target Pair