BDBM50167739 10-[4-(2-Dimethylamino-ethoxy)-benzyl]-10H-benzo[4,5]thieno[3,2-b]indole-3,7-diol::CHEMBL371072

SMILES: CN(C)CCOc1ccc(Cn2c3ccc(O)cc3c3sc4cc(O)ccc4c23)cc1

InChI Key: InChIKey=FQMDYRGPORXIJD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167739   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50167739 (10-[4-(2-Dimethylamino-ethoxy)-benzyl]-10H-benzo[4...) Show SMILES CN(C)CCOc1ccc(Cn2c3ccc(O)cc3c3sc4cc(O)ccc4c23)cc1 Show InChI InChI=1S/C25H24N2O3S/c1-26(2)11-12-30-19-7-3-16(4-8-19)15-27-22-10-6-17(28)13-21(22)25-24(27)20-9-5-18(29)14-23(20)31-25/h3-10,13-14,28-29H,11-12,15H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor beta				Bioorg Med Chem Lett 15: 2891-3 (2005) Article DOI: 10.1016/j.bmcl.2005.03.111 BindingDB Entry DOI: 10.7270/Q2JW8DDX
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50167739 (10-[4-(2-Dimethylamino-ethoxy)-benzyl]-10H-benzo[4...) Show SMILES CN(C)CCOc1ccc(Cn2c3ccc(O)cc3c3sc4cc(O)ccc4c23)cc1 Show InChI InChI=1S/C25H24N2O3S/c1-26(2)11-12-30-19-7-3-16(4-8-19)15-27-22-10-6-17(28)13-21(22)25-24(27)20-9-5-18(29)14-23(20)31-25/h3-10,13-14,28-29H,11-12,15H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitino of [3H]-17-beta-estradiol binding to human estrogen receptor alpha				Bioorg Med Chem Lett 15: 2891-3 (2005) Article DOI: 10.1016/j.bmcl.2005.03.111 BindingDB Entry DOI: 10.7270/Q2JW8DDX
					More data for this Ligand-Target Pair