null

SMILES: COc1ccc2cc(ccc2c1)-c1cc(nn1C(C)c1ccc(cc1)C(=O)N1CCC(C1)C(O)=O)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=KOAIFXVYRHSSKS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50168084 (CHEMBL3798548) Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1C(C)c1ccc(cc1)C(=O)N1CCC(C1)C(O)=O)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C34H29Cl2N3O4/c1-20(21-3-5-22(6-4-21)33(40)38-12-11-26(19-38)34(41)42)39-32(18-31(37-39)27-14-28(35)17-29(36)15-27)25-8-7-24-16-30(43-2)10-9-23(24)13-25/h3-10,13-18,20,26H,11-12,19H2,1-2H3,(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHO-K1 cells after 3 hrs by scintillation counting method				Bioorg Med Chem 24: 2852-63 (2016) BindingDB Entry DOI: 10.7270/Q27P919J
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50168084 (CHEMBL3798548) Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1C(C)c1ccc(cc1)C(=O)N1CCC(C1)C(O)=O)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C34H29Cl2N3O4/c1-20(21-3-5-22(6-4-21)33(40)38-12-11-26(19-38)34(41)42)39-32(18-31(37-39)27-14-28(35)17-29(36)15-27)25-8-7-24-16-30(43-2)10-9-23(24)13-25/h3-10,13-18,20,26H,11-12,19H2,1-2H3,(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Antagonist activity at wild type human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation incu...				Bioorg Med Chem 24: 2852-63 (2016) BindingDB Entry DOI: 10.7270/Q27P919J
					More data for this Ligand-Target Pair